Optimal variance estimation without estimating the mean function

We study the least squares estimator in the residual variance estimation context. We show that the mean squared differences of paired observations are asymptotically normally distributed. We further establish that, by regressing the mean squared differences of these paired observations on the squared distances between paired covariates via a simple least squares procedure, the resulting variance estimator is not only asymptotically normal and root-$n$ consistent, but also reaches the optimal bound in terms of estimation variance. We also demonstrate the advantage of the least squares estimator in comparison with existing methods in terms of the second order asymptotic properties.Comment: Published in at http://dx.doi.org/10.3150/12-BEJ432 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm

A Belief Propagation Based Framework for Soft Multiple-Symbol Differential Detection

Soft noncoherent detection, which relies on calculating the \textit{a posteriori} probabilities (APPs) of the bits transmitted with no channel estimation, is imperative for achieving excellent detection performance in high-dimensional wireless communications. In this paper, a high-performance belief propagation (BP)-based soft multiple-symbol differential detection (MSDD) framework, dubbed BP-MSDD, is proposed with its illustrative application in differential space-time block-code (DSTBC)-aided ultra-wideband impulse radio (UWB-IR) systems. Firstly, we revisit the signal sampling with the aid of a trellis structure and decompose the trellis into multiple subtrellises. Furthermore, we derive an APP calculation algorithm, in which the forward-and-backward message passing mechanism of BP operates on the subtrellises. The proposed BP-MSDD is capable of significantly outperforming the conventional hard-decision MSDDs. However, the computational complexity of the BP-MSDD increases exponentially with the number of MSDD trellis states. To circumvent this excessive complexity for practical implementations, we reformulate the BP-MSDD, and additionally propose a Viterbi algorithm (VA)-based hard-decision MSDD (VA-HMSDD) and a VA-based soft-decision MSDD (VA-SMSDD). Moreover, both the proposed BP-MSDD and VA-SMSDD can be exploited in conjunction with soft channel decoding to obtain powerful iterative detection and decoding based receivers. Simulation results demonstrate the effectiveness of the proposed algorithms in DSTBC-aided UWB-IR systems.Comment: 14 pages, 12 figures, 3 tables, accepted to appear on IEEE Transactions on Wireless Communications, Aug. 201

A statistical normalization method and differential expression analysis for RNA-seq data between different species

Background: High-throughput techniques bring novel tools but also statistical challenges to genomic research. Identifying genes with differential expression between different species is an effective way to discover evolutionarily conserved transcriptional responses. To remove systematic variation between different species for a fair comparison, the normalization procedure serves as a crucial pre-processing step that adjusts for the varying sample sequencing depths and other confounding technical effects. Results: In this paper, we propose a scale based normalization (SCBN) method by taking into account the available knowledge of conserved orthologous genes and hypothesis testing framework. Considering the different gene lengths and unmapped genes between different species, we formulate the problem from the perspective of hypothesis testing and search for the optimal scaling factor that minimizes the deviation between the empirical and nominal type I errors. Conclusions: Simulation studies show that the proposed method performs significantly better than the existing competitor in a wide range of settings. An RNA-seq dataset of different species is also analyzed and it coincides with the conclusion that the proposed method outperforms the existing method. For practical applications, we have also developed an R package named "SCBN" and the software is available at http://www.bioconductor.org/packages/devel/bioc/html/SCBN.html

Incorporating Intra-Class Variance to Fine-Grained Visual Recognition

Fine-grained visual recognition aims to capture discriminative characteristics amongst visually similar categories. The state-of-the-art research work has significantly improved the fine-grained recognition performance by deep metric learning using triplet network. However, the impact of intra-category variance on the performance of recognition and robust feature representation has not been well studied. In this paper, we propose to leverage intra-class variance in metric learning of triplet network to improve the performance of fine-grained recognition. Through partitioning training images within each category into a few groups, we form the triplet samples across different categories as well as different groups, which is called Group Sensitive TRiplet Sampling (GS-TRS). Accordingly, the triplet loss function is strengthened by incorporating intra-class variance with GS-TRS, which may contribute to the optimization objective of triplet network. Extensive experiments over benchmark datasets CompCar and VehicleID show that the proposed GS-TRS has significantly outperformed state-of-the-art approaches in both classification and retrieval tasks.Comment: 6 pages, 5 figure